          |
 |
< Previous | 2023 Agenda and Abstracts | Next >
2023 OMIG Abstract
Purpose: Neuropathic corneal pain (NCP) is caused by damage or disease of the somatosensory nervous system that innervates the cornea and presents with symptoms of pain or persistent unpleasant sensations, such as burning, dryness, or light sensitivity. NCP can also present with concomitant non-ocular facial pain. NCP significantly impacts patients' quality of life (QoL), but the additional role of non-ocular facial pain on QoL dimensions has not been studied to date. We aim to compare NCP patients who indicate minimal to those with moderate/severe facial pain and the impact of their pain on physical, psychological and social QoL dimensions.
Methods: A retrospective, cross-sectional, comparative study was conducted, including 65 NCP patients divided into 2 groups: Group 1 included NCP patients with none to mild non-ocular pain (score 0-3/10; n=25) and group 2 included NCP patients reporting moderate/severe non-ocular pain (score 4-10/10; n=40). Demographic features and ocular pain assessment survey (OPAS) scores (0-10) were reviewed. The OPAS comprises physical (vision-related), psychological and social dimensions of QoL through six items.
Results: Patients included 45 females and 20 males, aged 53.0±15.9 years. The mean ages of group 1 and group 2 were 54±15.9 and 53±16.2 years, respectively (p> 0.05). Patients in group 1 reported 1.08±0.23 non-ocular pain in the last 2 weeks as and group 2 patients had a 7.0±0.36 (p<0.0001). The mean most eye pain intensity scores (scale 0-10) in the last 2 weeks were 4.70±0.54 (group 1) and 5.58 ±0.55 group 2 (p=0.14), respectively. There was a significant (p=0.04) difference in the least eye pain intensity between group 1: 3.50±0.52 and group 2: 2.08±0.39. The interference of pain on physical (vision-related) dimension of QoL was: reading/computer (group 1: 5.65±0.67, group 2: 5.73±0.56 (p=0.93), driving/TV (group 1: 5.18±0.69, group 2: 4.38±0.52, p=0.36) and general activity (group 1: 3.21±0.61, group 2: 4.20±0.48, p=0.20). Mood (group 1: 4.74±0.75, group 2: 5.90±0.53 p=0.21) and sleep (group 1: 2.54±0.54, group 2: 4.08±0.51, p=0.04) for the psychological dimension; and enjoying life/social relations (group 1: 4.71±0.72, group 2: 5.49±0.55, p=0.39) for the social dimension of QoL.
Conclusions: Ocular pain perception in NCP patients with minimal or moderate/severe non-ocular facial pain is comparable, although the least pain is higher in patients with minimal non-ocular facial pain. NCP patients with minimal and moderate/severe non-ocular facial pain report comparable interference of their pain with QoL dimensions, except for interference with sleep that is higher in patients with non-ocular facial pain. Our results demonstrate that NCP alone, even without non-ocular facial pain, significantly interferes with all QoL dimensions.
Disclosure:
N (Mirzaee, Mekka, Lopez, Dieckmann, Koseoglu, Jamali, Cox);
C (Hamrah, Novartis, Dompe, Oysterpoint Pharma, OKYO
< Previous | 2023 Agenda and Abstracts | Next > |
|
